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Dyax Launches Hereditary Angioedema Genetic Counseling Program to Educate Patients and Family Members about Disease and Inherit


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Published in Health and Fitness on Wednesday, April 11th 2012 at 4:25 GMT by Market Wire   Print publication without navigation


BURLINGTON, Mass.--([ ])--[ Dyax Corp. ] (NASDAQ: DYAX) the manufacturer of KALBITOR (ecallantide) for the treatment of acute attacks of hereditary angioedema (HAE) in patients 16 years of age and older, has announced the launch of its HAE genetic counseling program. The program, which is available to all members of the HAE community, provides diagnosed HAE patients and their family members with a free counseling session.

"and we greatly appreciate Dyaxas efforts in this area."

aWe are pleased to bring this important resource to the HAE communitya, said Gustav Christensen, President and Chief Executive Officer of Dyax. aAs leaders in this community, we see the provision of these types of resources and support as an important way to help meet the needs of HAE patientsa.

Dyaxas genetic counseling program provides eligible HAE patients with access to board-certified and state licensed genetic counselors that are available nationally for phone, internet or in-person counseling sessions. The service includes an overview of the condition, family planning counseling and patient education and resources.

"The HAEA supports all efforts to help HAE patientsa, said Janet Long, Executive Vice President, US Hereditary Angioedema Association, "and we greatly appreciate Dyaxas efforts in this area."

Patients can enroll in theprogram by calling 855-HAE Hope (855-423-4674) or by visiting [ http://www.haehope.com/haegeneticcounseling ]. The HAE genetic counseling program is just part of a suite of services that Dyax provides to HAE patients. To learn more about other Dyax programs and services, please contact 855-423-4674 or visit [ www.dyax.com ].

About HAE

Hereditary angioedema (HAE) is a rare acute inflammatory condition characterized by episodes of severe, often painful swelling affecting the extremities, gastrointestinal tract, genitalia, and larynx. HAE is caused by low or dysfunctional levels of C1 esterase inhibitor (C1-INH), a naturally occurring molecule that inhibits plasma kallikrein, a key mediator of inflammation, and other serine proteases in the blood. HAE is estimated to affect 1 in 10,000 to 1 in 50,000 individuals. Learn more at [ www.HAEHope.com ].

About KALBITOR (ecallantide)

KALBITOR is a plasma kallikrein inhibitor indicated for the treatment of acute attacks of hereditary angioedema (HAE) in patients 16 years of age and older. KALBITOR, which was discovered and developed by Dyax, is the first subcutaneous treatment available in the U.S. for treating acute HAE attacks.

Important KALBITOR Safety Information

Anaphylaxis has been reported after administration of KALBITOR. Because of the risk of anaphylaxis, KALBITOR should only be administered by a healthcare professional with appropriate medical support to manage anaphylaxis and hereditary angioedema. Healthcare professionals should be aware of the similarity of symptoms between hypersensitivity reactions and hereditary angioedema and patients should be monitored closely. KALBITOR should not be administered to patients with known clinical hypersensitivity to KALBITOR.

For more information about KALBITOR, including full prescribing information, visit [ www.KALBITOR.com ].

About Dyax

Dyax is a fully integrated biopharmaceutical company focused on the development and commercialization of novel biotherapeutics for unmet medical needs. Dyax's lead product, ecallantide, has been approved under the brand name KALBITOR in the United States for the treatment of acute attacks of hereditary angioedema (HAE) in patients 16 years of age and older.

Dyax is commercializing KALBITOR in the United States independently, and establishing strategic collaborations to develop and commercialize ecallantide for the treatment of HAE in key regions worldwide. Currently, Dyax has agreements for regions including Europe, Japan, Russia, the Middle East, Israel, North Africa, Australia, New Zealand, Latin America (excluding Mexico) and the Caribbean. Dyax is also exploring other potential indications for ecallantide, either alone or through collaborations, including drug-induced angioedema.

Ecallantide and other compounds in Dyax's pipeline were identified using its patented phage display technology, which rapidly selects compounds that bind with high affinity and specificity to therapeutic targets. Dyax leverages this technology broadly through the Licensing and Funded Research Program (LFRP), which has over 70 revenue generating licenses and collaborations for therapeutic discovery, as well as for affinity separations, diagnostic imaging, and research reagents. The success of the Company's LFRP portfolio is illustrated by the program's advanced licensee pipeline that includes 18 candidates in clinical development. Of those candidates, four are in Phase 3 clinical trials, four are in Phase 2 and ten are in Phase 1.

Dyax is headquartered in Burlington, Massachusetts. For online information about Dyax Corp., please visit [ www.dyax.com ].


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