Tue, April 16, 2013
Mon, April 15, 2013
Fri, April 12, 2013
Thu, April 11, 2013
[ Thu, Apr 11th 2013 ]: Market Wire
15 PM EDT
Wed, April 10, 2013
Tue, April 9, 2013
[ Tue, Apr 09th 2013 ]: Market Wire
30 a.m. ET
Mon, April 8, 2013
Sat, April 6, 2013
Fri, April 5, 2013
Thu, April 4, 2013
Wed, April 3, 2013
Tue, April 2, 2013
Mon, April 1, 2013
Fri, March 29, 2013
Thu, March 28, 2013
Wed, March 27, 2013
Tue, March 26, 2013
Mon, March 25, 2013
Sun, March 24, 2013
Fri, March 22, 2013
Thu, March 21, 2013
Wed, March 20, 2013
[ Wed, Mar 20th 2013 ]: Market Wire
00am ET
Tue, March 19, 2013
Mon, March 18, 2013

Merrimack Pharmaceuticals To Present Preclinical Research On Five Novel Cancer Therapies


//health-fitness.news-articles.net/content/2013/ .. cal-research-on-five-novel-cancer-therapies.html
Published in Health and Fitness on by Market Wire   Print publication without navigation



Merrimack Pharmaceuticals To Present Preclinical Research On Five Novel Cancer Therapies -- CAMBRIDGE, Mass., April 2, 2013 /PRNewswire/ --

CAMBRIDGE, Mass., April 2, 2013 /PRNewswire/ -- Merrimack Pharmaceuticals, Inc. (NASDAQ: [ MACK ]) today announced that research data on five novel experimental cancer therapies (MM-398, MM-121, MM-111, MM-302, and MM-141) will be presented at the 2013 American Association for Cancer Research (AACR) Annual Meeting, April 6-10, 2013 in Washington, DC.  Presentations will include preclinical data evaluating the potential of treatments to restore tumor drug sensitivity and delay resistance when used alone or in combination with other targeted treatments.  Data will be shared in late-breaking sessions, mini-symposia and poster sessions.

"We are excited about the advancements and research to be presented regarding several of the therapies in Merrimack's robust oncology pipeline," said Ulrik Nielsen , PhD, Co-Founder and Chief Scientific Officer, Merrimack Pharmaceuticals. "The research explores the potential of our novel medicines to inhibit signaling to prevent tumor growth and improve responsiveness to treatments, as well as the potential of our investigational nanotherapeutics to deliver chemotherapy directly to diseased cells to enhance activity and improve safety. These therapies are being studied across multiple cancers such as head and neck, lung, breast, gastric, pancreatic and melanoma."

Late-Breaking Poster

  • Session Title: Late-Breaking Research - Clinical Research 1
    LB-79: Combined treatment with HER3 antibody MM-121/SAR 256212 and EGFR antibody cetuximab in pre-clinical models of head and neck cancer
    Monday, April 8, 2013, 1:00 PM - 5:00 PM
    Hall A-C, Poster Section 45

Mini-Symposium Presentations

  • Session Title: Preclinical and Molecular Endocrinology in Hormone-Responsive Cancers
    1072: MM-121/SAR256212, an anti-ErbB3 antibody, restores sensitivity to letrozole and delays the onset of resistance in an ER+ breast cancer model
    Sunday, April 7, 2013, 4:05 PM - 4:20 PM
    Room 206, Washington Convention Center
  • Session Title: Novel Targeted Therapies 2
    4633: MM-111, a bispecific HER2 and HER3 antibody, synergistically combines with trastuzumab and paclitaxel in preclinical models of gastric cancer
    Tuesday, April 9, 2013, 3:05 PM - 3:20 PM
    Room 152, Washington Convention Center

Poster Sessions

  • Session Title: Experimental Combination Therapy 1
    2077A: MM-141, a novel bispecific antibody co-inhibitor of IGF-1R and ErbB3, inhibits the proliferation of melanoma cells
    Monday, April 8, 2013, 1:00 PM -5:00 PM
    Hall A-C, Poster Section 37
  • Session Title: Experimental Combination Therapy 2
    3271: Tumor priming with cyclophosphamide increases delivery and activity of Her2-targeted liposomal doxorubicin (MM-302) in preclinical models of breast cancer
    Tuesday, April 9, 2013, 8:00 AM -12:00 PM
    Hall A-C, Poster Section 37
  • Session Title: Novel Delivery Technologies
    5622: The tumor microenvironment modulates the delivery and activation of liposomal encapsulated irinotecan, MM-398
    Wednesday, April 10, 2013, 8:00 AM -12:00 PM
    Hall A-C, Poster Section 41
  • Session Title: Antibody/Protein Therapeutics
    5464: In-vitro studies of MM-121/SAR 256212, an anti-ErbB-3 antibody, in combination with erlotinib in EGFR-wild-type NSCLC
    Wednesday, April 10, 2013, 8:00 AM -12:00 PM
    Hall A-C, Poster Section 36

Sanofi and Merrimack entered into an exclusive, licensing and global collaboration agreement for MM-121 in 2009.

About Merrimack Pharmaceuticals, Inc.
Merrimack Pharmaceuticals is a biopharmaceutical company discovering, developing and preparing to commercialize innovative medicines paired with companion diagnostics for the treatment of cancer. Merrimack applies Network Biology, its proprietary systems biology-based approach to biomedical research, throughout the research and development process. Merrimack currently has six targeted therapeutic oncology candidates in clinical development.

Forward-Looking Statement
Any statements in this press release about future expectations, plans and prospects for Merrimack constitute forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995, as amended. Actual results may differ materially from those indicated by such forward-looking statements. Merrimack anticipates that subsequent events and developments will cause its views to change. However, while Merrimack may elect to update these forward-looking statements at some point in the future, Merrimack specifically disclaims any obligation to do so.

SOURCE Merrimack Pharmaceuticals, Inc.




Publication Contributing Sources

Publication Sponsors
[ Last Sunday ] - Oceanside Rental Gear