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Quest PharmaTech Acquires Late-Stage Immunotherapeutic Antibody Pipeline
//health-fitness.news-articles.net/content/2009/ .. e-stage-immunotherapeutic-antibody-pipeline.html
Published in Health and Fitness on Wednesday, September 30th 2009 at 10:26 GMT, Last Modified on 2009-11-02 11:43:12 by Market Wire
Published in Health and Fitness on Wednesday, September 30th 2009 at 10:26 GMT, Last Modified on 2009-11-02 11:43:12 by Market Wire

- Combination with chemotherapy: A recent 40-patient randomized clinical trial (Journal of Immunotherapy, 2009, Volume 32, page 54- 65) established that front-line carboplatin-paclitaxel chemotherapy has immune adjuvant properties when administered concurrent to the anti-CA125 antibody, and immunity is enhanced relative to that which is achievable in an antibody treatment alone; - Combination with photodynamic therapy: In recent preclinical studies done at the BC Cancer Agency (Photochemistry and Photobiology, 2009, DOI:1111, European Patent No. 1,357,944), Quest showed that the therapeutic outcome of SL052 mediated photodynamic therapy can be improved by a combination with antibody mediated immunotherapy; and - Combination with radioimmuno therapy: The use of Oregovomab, radiolabeled with an appropriate therapeutic isotope, has the potential to provide the benefits of antibody mediated immune response as well as antigen-bearing tumor cell radiotoxicity. Such a concept has already been established in a preclinical setting (Applied Radiation and Isotopes, 1997, Volume 48, pages 899-906).
"Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release."
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