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Cancer Survivors Benefit from Increased Physical Activity

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  Published in Health and Fitness on Tuesday, February 24th 2026 at 10:56 GMT by Daily

Tuesday, February 24th, 2026 - A groundbreaking study published in the Journal of the American Medical Association (JAMA) provides compelling evidence that increased leisure-time physical activity (LTPA) following a cancer diagnosis is strongly linked to a significantly lower risk of mortality. The research, utilizing data from the extensive National Institutes of Health's All of Us Research Program, offers a hopeful message for the millions living with cancer worldwide.

The study meticulously tracked over 65,000 cancer survivors, analyzing their self-reported LTPA levels and correlating them with mortality rates over an average of four years. Participants were categorized based on activity levels: low, moderate, high, and very high. The results paint a clear picture - consistent physical activity isn't just beneficial for cancer survivors, it's potentially life-extending.

Researchers found that compared to those reporting low levels of LTPA, individuals in the high activity group experienced a 13% reduction in mortality risk. Even more remarkably, those categorized as having "very high" levels of leisure-time physical activity demonstrated a substantial 24% lower risk of death. Dr. Robin Jenkins, lead author of the study and a clinical research fellow at the University of Oxford, emphasized the practical implications of these findings. "Our findings suggest that even relatively small increases in LTPA after a cancer diagnosis may lead to meaningful reductions in mortality risk," she stated.

This isn't simply about strenuous workouts. LTPA encompasses a wide range of activities, from brisk walking and gardening to cycling and swimming - exercises that many individuals can realistically incorporate into their daily routines. The study's strength lies in its large sample size and its observation across a diverse range of cancer types and stages. The positive correlation between activity and survival remained consistent regardless of the specific cancer diagnosis or how advanced the disease was at the time of diagnosis, highlighting the broad applicability of these findings.

Beyond Survival: Improving Quality of Life

While the study primarily focused on mortality rates, experts believe the benefits of exercise extend far beyond simply living longer. Physical activity plays a crucial role in mitigating many of the debilitating side effects associated with cancer and its treatment. These include fatigue, muscle weakness, loss of bone density, anxiety, and depression. Exercise can help restore physical function, improve energy levels, and enhance overall quality of life, allowing survivors to regain control and independence.

"We often tell patients to 'do what you can,' but this study gives us more concrete data to support that advice," explains Dr. Eleanor Vance, a leading oncologist not involved in the JAMA study. "It reinforces the idea that exercise isn't just a 'nice-to-have' for cancer survivors; it's an integral part of comprehensive care."

Important Considerations and Future Research

It's important to acknowledge that this is an observational study, meaning it cannot definitively prove a cause-and-effect relationship. While the correlation between LTPA and lower mortality is strong, other factors could potentially contribute to the observed results. Dr. Jenkins rightly points out that "More research is needed to confirm these findings," and to better understand the optimal types, intensity, and duration of exercise for different cancer types and patient populations.

Furthermore, it's critical that cancer survivors consult with their healthcare team before starting any new exercise program. Individualized recommendations are essential, taking into account factors such as the type of cancer, treatment received, current fitness level, and any pre-existing medical conditions. A qualified exercise professional experienced in working with cancer patients can help develop a safe and effective exercise plan.

The All of Us Research Program continues to collect valuable data, and future analyses are expected to delve deeper into the specific mechanisms by which physical activity impacts cancer survival. Researchers are also exploring the potential of incorporating exercise interventions into standard cancer care protocols.

This latest research serves as a powerful reminder that even in the face of a serious illness, individuals can take proactive steps to improve their health and well-being. By prioritizing physical activity, cancer survivors can empower themselves to live longer, healthier, and more fulfilling lives.

Source: Medical Dialogues [ https://medicaldialogues.in/oncology/news/higher-levels-of-leisure-time-physical-activity-after-diagnosis-of-cancer-linked-to-lower-mortality-jama-165319 ]