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Excess weight hikes risk of health double-whammy among older women


🞛 This publication is a summary or evaluation of another publication 🞛 This publication contains editorial commentary or bias from the source
July 8 (UPI) -- Older women carrying excess weight have a higher risk of a life-threatening double-whammy, a new study says.

The central focus of the article is a study published on October 24, 2023, in the *Journal of the National Cancer Institute*, which reveals that older women with excess weight face a significantly heightened risk of experiencing a "double whammy" of health issues—namely, breast cancer followed by cardiovascular disease. The research, led by Dr. Heather Spencer Feigelson, a senior investigator at the Kaiser Permanente Colorado Institute for Health Research, analyzed data from nearly 5,000 women who were diagnosed with breast cancer between 2005 and 2019. These women were part of the Pathways Study, a long-term research initiative tracking breast cancer survivors. The study specifically examined the relationship between body mass index (BMI) at the time of breast cancer diagnosis and the subsequent risk of developing cardiovascular issues such as heart disease, heart failure, or stroke.
One of the most striking findings from the study is that women classified as overweight or obese at the time of their breast cancer diagnosis were far more likely to develop cardiovascular disease in the years following their cancer treatment. Specifically, women with a BMI of 25 to 29.9 (categorized as overweight) had a 19% higher risk of cardiovascular disease compared to women with a normal BMI (18.5 to 24.9). For women with a BMI of 30 or higher (classified as obese), the risk escalated dramatically, with a 57% higher likelihood of developing cardiovascular issues. This correlation held even after adjusting for other risk factors such as age, smoking status, physical activity levels, and pre-existing health conditions like diabetes or hypertension.
The article explains that the connection between excess weight, breast cancer, and cardiovascular disease is multifaceted. Obesity is a well-established risk factor for both breast cancer and heart disease independently, but the study highlights how these risks compound in older women who survive breast cancer. Breast cancer treatments, such as chemotherapy and radiation, can themselves contribute to cardiovascular damage, particularly when combined with the physiological stress of excess weight. Additionally, obesity is associated with chronic inflammation and metabolic dysfunction, both of which exacerbate the risk of heart disease and may promote cancer recurrence or progression. The article quotes Dr. Feigelson, who emphasizes that "obesity is a persistent risk factor for both breast cancer survivors and for cardiovascular disease," underscoring the need for targeted interventions in this population.
Beyond the statistical findings, the article explores the broader implications of these health risks for older women. Breast cancer is one of the most common cancers among women, with survival rates having improved significantly over recent decades due to advances in early detection and treatment. However, as more women survive breast cancer, they face an increased likelihood of developing other chronic conditions, particularly cardiovascular disease, which remains the leading cause of death among women in the United States. The study suggests that excess weight acts as a critical modifier in this equation, amplifying the risk of secondary health issues and potentially reducing overall survival and quality of life for breast cancer survivors.
The article also touches on the mechanisms behind the observed link between obesity and the dual burden of breast cancer and cardiovascular disease. Excess body fat, particularly visceral fat, is known to produce hormones and inflammatory markers that can fuel cancer growth and contribute to atherosclerosis (the buildup of plaques in arteries), a key driver of heart disease. Furthermore, older women are already at an elevated risk for both conditions due to age-related declines in metabolic health and hormonal changes post-menopause, which can exacerbate the effects of obesity. The combination of these factors creates a vicious cycle, where excess weight not only increases the likelihood of breast cancer but also heightens the risk of cardiovascular complications during and after cancer treatment.
In terms of actionable insights, the article stresses the importance of weight management as a preventive strategy for older women, both before and after a breast cancer diagnosis. Dr. Feigelson notes that maintaining a healthy weight through diet and exercise could significantly reduce the risk of both initial breast cancer diagnoses and subsequent cardiovascular events. However, the article acknowledges the challenges of weight loss, particularly for older adults who may face mobility issues, metabolic slowdown, or psychological barriers following a cancer diagnosis. It suggests that healthcare providers should prioritize personalized interventions, such as nutritional counseling and physical therapy, to support weight management in this vulnerable population.
The piece also highlights the need for greater awareness among breast cancer survivors and their healthcare teams about the long-term risks of cardiovascular disease. While much of the focus during cancer treatment is on eradicating the disease, the study underscores the importance of post-treatment care that addresses cardiovascular health. This includes regular screenings for heart disease risk factors (such as high blood pressure and cholesterol levels), as well as lifestyle interventions to mitigate the impact of excess weight. The article suggests that integrating cardiovascular risk assessment into routine follow-up care for breast cancer survivors could help identify at-risk individuals early and prevent life-threatening complications.
In a broader context, the findings of this study contribute to the growing body of evidence linking obesity to a range of chronic health conditions, particularly in aging populations. The article notes that obesity rates have been rising globally, with significant implications for public health. In the United States alone, more than 40% of adults are classified as obese, and the prevalence is even higher among older adults due to age-related weight gain and reduced physical activity. For older women, who are already at heightened risk for breast cancer and heart disease, the added burden of excess weight represents a major public health challenge that requires coordinated efforts from policymakers, healthcare providers, and communities.
The article concludes by emphasizing the urgency of addressing obesity as a modifiable risk factor in older women. It calls for increased research into the long-term health outcomes of breast cancer survivors, as well as the development of targeted interventions to reduce the dual burden of cancer and cardiovascular disease. While the study focused specifically on women with breast cancer, the findings have broader implications for all older adults, highlighting the critical role of weight management in preventing chronic disease and improving overall health outcomes.
In summary, "Excess Weight Hikes Risk of Health Double Whammy Among Older Women" provides a detailed examination of the compounded health risks faced by older women with excess weight, particularly those diagnosed with breast cancer. The article draws on a robust study to illustrate how obesity significantly increases the likelihood of developing cardiovascular disease following a breast cancer diagnosis, with risks escalating alongside higher BMI levels. It explores the biological mechanisms behind this link, the challenges of weight management in older adults, and the need for integrated healthcare approaches to address both cancer and cardiovascular risks. By shedding light on this critical intersection of health issues, the article underscores the importance of prevention, awareness, and personalized care in improving the long-term health and survival of older women. This comprehensive discussion not only informs readers about a pressing health concern but also serves as a call to action for better support and resources for aging populations grappling with the dual burden of chronic conditions.
Read the Full UPI Article at:
[ https://www.msn.com/en-us/health/medical/excess-weight-hikes-risk-of-health-double-whammy-among-older-women/ar-AA1IdBdK ]
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